This section publishes research on the variety and impact of chromosomal aberrations on all types of human cancer. Manuscripts on animal models of tumors are also welcome. Case reports can only be considered if they provide a comprehensive review of the literature or describe an as yet-unreported finding in the corresponding malignancy. The exclusive use of molecular cytogenetic approaches (including array-CGH), or a combination of those with banding cytogenetics, standard molecular genetic or modern high-throughput approaches, or with proteomic or epigenetic studies, is welcome.
Acute myeloid leukemia with inv(16)(p13.1q22) and deletion of the 5’MYH11/3’CBFB gene fusion: a report of two cases and literature review
Abnormalities of chromosome 16 are found in about 5–8% of acute myeloid leukemia (AML). The AML with inv(16)(p13.1q22) or t (16;16)(p13.1;q22) is associated with a high rate of complete remission (CR) and favo...
Citation: Molecular Cytogenetics 2020 13:4