This section publishes research on the variety and impact of chromosomal aberrations on all types of human cancer. Manuscripts on animal models of tumors are also welcome. Case reports can only be considered if they provide a comprehensive review of the literature or describe an as yet-unreported finding in the corresponding malignancy. The exclusive use of molecular cytogenetic approaches (including array-CGH), or a combination of those with banding cytogenetics, standard molecular genetic or modern high-throughput approaches, or with proteomic or epigenetic studies, is welcome.
A new childhood ALL case with an extremely complex karyotype and acute spontaneous tumor lysis syndrome
B cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood, with, after corresponding treatment, an overall complete remission rate of 90%. Approximately 75% of B-ALL case...
Citation: Molecular Cytogenetics 2020 13:44