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Mutagenesis

Section information

Even though the development of genome-wide techniques has rapidly improved, mutagenesis can still be best assessed at the single-cell level using molecular cytogenetics. Corresponding research and review articles are welcome.

  1. Environmental risk factors have been shown to alter DNA copy number variations (CNVs). Recently, CNVs have been described to arise after low-dose ionizing radiation in vitro and in vivo. Development of cost- a...

    Authors: Tigran Harutyunyan, Galina Hovhannisyan, Anzhela Sargsyan, Bagrat Grigoryan, Ahmed H. Al-Rikabi, Anja Weise, Thomas Liehr and Rouben Aroutiounian

    Citation: Molecular Cytogenetics 2019 12:18

    Content type: Research

    Published on:

  2. Duchenne muscular dystrophy (DMD) is an X-linked recessive muscle-wasting disease caused by a mutation in the DMD gene. The aim of this study was to identify a de novo mutation of the DMD gene in the family of a ...

    Authors: Beibei Wu, Liying Wang, Ting Dong, Jiahui Jin, Yili Lu, Huiping Wu, Yue Luo and Xiaoou Shan

    Citation: Molecular Cytogenetics 2017 10:8

    Content type: Research

    Published on:

  3. Fanconi anemia (FA) is a chromosomal instability syndrome characterized by increased frequency of chromosomal breakages, chromosomal radial figures and accelerated telomere shortening. In this work we performe...

    Authors: Jelena Filipović, Gordana Joksić, Dragana Vujić, Ivana Joksić, Kristin Mrasek, Anja Weise and Thomas Liehr

    Citation: Molecular Cytogenetics 2016 9:70

    Content type: Research

    Published on:

  4. Micronucleus (MN) assay is a well standardized approach for evaluation of clastogenic/aneugenic effects of mutagens. Fluorescence in situ hybridization (FISH) is successfully used to characterize the chromosom...

    Authors: Galina Hovhannisyan, Rouben Aroutiounian, Nelly Babayan, Tigran Harutyunyan and Thomas Liehr

    Citation: Molecular Cytogenetics 2016 9:49

    Content type: Research

    Published on:

  5. Painters are exposed to an extensive variety of harmful substances like aromatic hydrocarbons used as solvents and paint removers, some of which have shown clastogenic activity. These substances constitute a c...

    Authors: Mónica Villalba-Campos, Lilian Chuaire-Noack, Magda Carolina Sánchez-Corredor and Milena Rondón-Lagos

    Citation: Molecular Cytogenetics 2016 9:46

    Content type: Research

    Published on:

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