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Even though the development of genome-wide techniques has rapidly improved, mutagenesis can still be best assessed at the single-cell level using molecular cytogenetics. Corresponding research and review articles are welcome.

  1. Content type: Research

    Environmental risk factors have been shown to alter DNA copy number variations (CNVs). Recently, CNVs have been described to arise after low-dose ionizing radiation in vitro and in vivo. Development of cost- a...

    Authors: Tigran Harutyunyan, Galina Hovhannisyan, Anzhela Sargsyan, Bagrat Grigoryan, Ahmed H. Al-Rikabi, Anja Weise, Thomas Liehr and Rouben Aroutiounian

    Citation: Molecular Cytogenetics 2019 12:18

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  2. Content type: Research

    Duchenne muscular dystrophy (DMD) is an X-linked recessive muscle-wasting disease caused by a mutation in the DMD gene. The aim of this study was to identify a de novo mutation of the DMD gene in the family of a ...

    Authors: Beibei Wu, Liying Wang, Ting Dong, Jiahui Jin, Yili Lu, Huiping Wu, Yue Luo and Xiaoou Shan

    Citation: Molecular Cytogenetics 2017 10:8

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  3. Content type: Research

    Fanconi anemia (FA) is a chromosomal instability syndrome characterized by increased frequency of chromosomal breakages, chromosomal radial figures and accelerated telomere shortening. In this work we performe...

    Authors: Jelena Filipović, Gordana Joksić, Dragana Vujić, Ivana Joksić, Kristin Mrasek, Anja Weise and Thomas Liehr

    Citation: Molecular Cytogenetics 2016 9:70

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  4. Content type: Research

    Micronucleus (MN) assay is a well standardized approach for evaluation of clastogenic/aneugenic effects of mutagens. Fluorescence in situ hybridization (FISH) is successfully used to characterize the chromosom...

    Authors: Galina Hovhannisyan, Rouben Aroutiounian, Nelly Babayan, Tigran Harutyunyan and Thomas Liehr

    Citation: Molecular Cytogenetics 2016 9:49

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  5. Content type: Research

    Painters are exposed to an extensive variety of harmful substances like aromatic hydrocarbons used as solvents and paint removers, some of which have shown clastogenic activity. These substances constitute a c...

    Authors: Mónica Villalba-Campos, Lilian Chuaire-Noack, Magda Carolina Sánchez-Corredor and Milena Rondón-Lagos

    Citation: Molecular Cytogenetics 2016 9:46

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