The impact of nuclear architecture is neither well studied nor well understood. Molecular cytogenetics is the best approach for studying the impact of chromosomal aberrations, as it is single cell-directed. This section publishes original research on the 3D structure of chromosomes and interphase nuclei. Small movies can also be provided here as supplementary files to Molecular Cytogenetics.
Dynamic nature of somatic chromosomal mosaicism, genetic-environmental interactions and therapeutic opportunities in disease and aging
Somatic chromosomal mosaicism is the presence of cell populations differing with respect to the chromosome complements (e.g. normal and abnormal) in an individual. Chromosomal mosaicism is associated with a wi...
Citation: Molecular Cytogenetics 2020 13:16