The impact of nuclear architecture is neither well studied nor well understood. Molecular cytogenetics is the best approach for studying the impact of chromosomal aberrations, as it is single cell-directed. This section publishes original research on the 3D structure of chromosomes and interphase nuclei. Small movies can also be provided here as supplementary files to Molecular Cytogenetics.
About classical molecular genetics, cytogenetic and molecular cytogenetic data not considered by Genome Reference Consortium and thus not included in genome browsers like UCSC, Ensembl or NCBI
The Genome Reference Consortium (GRC) has according to its own statement the “mission to improve the human reference genome assembly, correcting errors and adding sequence to ensure it provides the best repres...
Citation: Molecular Cytogenetics 2021 14:20