The impact of nuclear architecture is neither well studied nor well understood. Molecular cytogenetics is the best approach for studying the impact of chromosomal aberrations, as it is single cell-directed. This section publishes original research on the 3D structure of chromosomes and interphase nuclei. Small movies can also be provided here as supplementary files to Molecular Cytogenetics.
Rare cytogenetic abnormalities and their clinical relevance in pediatric acute leukemia of Saudi Arabian population
Childhood Acute Leukemia (AL) is characterized by recurrent genetic aberrations in 60% of AML cases and 90% of ALL cases. Insufficient data exists of rare cytogenetic abnormalities in AL. Therefore, we tested ...
Citation: Molecular Cytogenetics 2019 12:42