Publisher Correction: Is DNA methylation the new guardian of the genome?

Correction

In the original publication of this article [1] the figures and the captions of 3 figures do not match correctly due to a typographical error. In this correction article the corrected figures and captions for Figs. 1, 2 and 3 are shown.

Fig. 1

Rates of transmethylation of human tumor cell lines and normal human fibroblast cell strains. All cells were labeled with 100 μM [³⁵S]-methionine-containing medium (25 μCi/ml) for 24 h. Periodateoxidized 3-deazaadenosine was added to a concentration of 10 µM and the accumulation of [³⁵S] AdoHcy was measured at half- hour intervals. Solid lines are human cancer cell lines. Dashed lines are human normal cell strains [38]

Fig. 2

Recombinant methioninase (rMETase) traps cancer cells in S/G₂ phase. Time-course imaging of HeLa-FUCCI cells treated with rMETase (1.0 unit/ml). Kinetics of rMETase trapping of cells in S/G₂. Images were acquired with the FV1000 confocal microscope (Olympus, Tokyo, Japan). In the FUCCI system, the cells in G₀/G₁, S, or G₂/M phases appear red, yellow, or green, respectively [66]

Fig. 3

Efficacy of recombinant methioninase (rMETase) on growth of human colon tumors HCT 15 in nude mice. rMETase (5 or 10 units/g every 8 h) was administered by i.p. injection in nude mice with human colon tumor HCT 15, growing s.c. [54]

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