Durie BG, et al. International uniform response criteria for multiple myeloma. Leukemia. 2006;20(9):1467–73.
Article
CAS
PubMed
Google Scholar
Morgan GJ, Walker BA, Davies FE. The genetic architecture of multiple myeloma. Nat Rev Cancer. 2012;12(5):335–48.
Article
CAS
PubMed
Google Scholar
Sonneveld P, et al. Bortezomib-based versus nonbortezomib-based induction treatment before autologous stem-cell transplantation in patients with previously untreated multiple myeloma: a meta-analysis of phase III randomized, controlled trials. J Clin Oncol. 2013;31(26):3279–87.
Article
CAS
PubMed
Google Scholar
Laubach J, et al. Management of relapsed multiple myeloma: recommendations of the international myeloma working group. Leukemia. 2016;30(5):1005–17.
Article
CAS
PubMed
Google Scholar
Chapman MA, et al. Initial genome sequencing and analysis of multiple myeloma. Nature. 2011;471(7339):467–72.
Article
CAS
PubMed
PubMed Central
Google Scholar
Egan JB, et al. Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides. Blood. 2012;120(5):1060–6.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mikulasova A, et al. Genomewide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance. Eur J Haematol. 2016;97(6):568–75.
Article
CAS
PubMed
Google Scholar
Mikulasova A, et al. Somatic mutation spectrum in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape compared to multiple myeloma. Haematologica. 2017;
Walker BA, et al. A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value. Blood. 2010;116(15):e56–65.
Article
CAS
PubMed
Google Scholar
Walker BA, et al. Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma. Blood. 2006;108(5):1733–43.
Article
CAS
PubMed
Google Scholar
Keats JJ, et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell. 2007;12(2):131–44.
Article
CAS
PubMed
PubMed Central
Google Scholar
Keats JJ, et al. Clonal competition with alternating dominance in multiple myeloma. Blood. 2012;120(5):1067–76.
Article
CAS
PubMed
PubMed Central
Google Scholar
Heng HH, et al. Evolutionary mechanisms and diversity in cancer. Adv Cancer Res. 2011;112:217–53.
Article
CAS
PubMed
Google Scholar
Liu G, et al. Genome chaos: survival strategy during crisis. Cell Cycle. 2014;13(4):528–37.
Article
CAS
PubMed
Google Scholar
Stephens PJ, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell. 2011;144(1):27–40.
Article
CAS
PubMed
PubMed Central
Google Scholar
Kloosterman WP, et al. Constitutional chromothripsis rearrangements involve clustered double-stranded DNA breaks and nonhomologous repair mechanisms. Cell Rep. 2012;1(6):648–55.
Article
CAS
PubMed
Google Scholar
Skuja E, et al. Chromothripsis and progression-free survival in metastatic colorectal cancer. Mol Clin Oncol. 2017;6(2):182–6.
Article
PubMed
PubMed Central
Google Scholar
Smida J, et al. Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma. Int J Cancer. 2017;141(4):816–28.
Article
CAS
PubMed
Google Scholar
Middelkamp S, et al. Molecular dissection of germline chromothripsis in a developmental context using patient-derived iPS cells. Genome Med. 2017;9(1):9.
Article
PubMed
PubMed Central
Google Scholar
Magrangeas F, et al. Chromothripsis identifies a rare and aggressive entity among newly diagnosed multiple myeloma patients. Blood. 2011;118(3):675–8.
Article
CAS
PubMed
PubMed Central
Google Scholar
Cumova J, et al. Optimization of immunomagnetic selection of myeloma cells from bone marrow using magnetic activated cell sorting. Int J Hematol. 2010;92(2):314–9.
Article
CAS
PubMed
Google Scholar
Rajan AM, Rajkumar SV. Interpretation of cytogenetic results in multiple myeloma for clinical practice. Blood Cancer J. 2015;5:e365.
Article
CAS
PubMed
PubMed Central
Google Scholar
Palumbo A, et al. Revised international staging system for multiple myeloma: a report from international myeloma working group. J Clin Oncol. 2015;33(26):2863–9.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fonseca R, et al. International myeloma working group molecular classification of multiple myeloma: spotlight review. Leukemia. 2009;23(12):2210–21.
Article
CAS
PubMed
PubMed Central
Google Scholar
Fonseca R, et al. The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma. Blood. 2003;102(7):2562–7.
Article
CAS
PubMed
Google Scholar
Nemec P, et al. Gain of 1q21 is an unfavorable genetic prognostic factor for multiple myeloma patients treated with high-dose chemotherapy. Biol Blood Marrow Transplant. 2010;16(4):548–54.
Article
CAS
PubMed
Google Scholar
Greslikova H, et al. Negative prognostic significance of two or more cytogenetic abnormalities in multiple myeloma patients treated with autologous stem cell transplantation. Neoplasma. 2010;57(2):111–7.
Article
CAS
PubMed
Google Scholar
Smetana J, et al. Gain(1)(q21) is an unfavorable genetic prognostic factor for patients with relapsed multiple myeloma treated with thalidomide but not for those treated with bortezomib. Clin Lymphoma Myeloma Leuk. 2013;13(2):123–30.
Article
CAS
PubMed
Google Scholar
Lagana A, et al. Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma. Leukemia. 2018;32(1):120–30. https://doi.org/10.1038/leu.2017.197.
Lohr JG, et al. Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy. Cancer Cell. 2014;25(1):91–101.
Article
CAS
PubMed
PubMed Central
Google Scholar
Sonneveld P, et al. Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the international myeloma working group. Blood. 2016;127(24):2955–62.
Article
CAS
PubMed
PubMed Central
Google Scholar
Poot M. Of simple and complex genome rearrangements, Chromothripsis, Chromoanasynthesis, and chromosome chaos. Mol Syndromol. 2017;8(3):115–7.
Article
PubMed
PubMed Central
Google Scholar
Kloosterman WP, Koster J, Molenaar JJ. Prevalence and clinical implications of chromothripsis in cancer genomes. Curr Opin Oncol. 2014;26(1):64–72.
Article
CAS
PubMed
Google Scholar
Smetana J, et al. Genome-wide screening of cytogenetic abnormalities in multiple myeloma patients using array-CGH technique: a Czech multicenter experience. Biomed Res Int. 2014;2014:209670.
Article
PubMed
PubMed Central
Google Scholar
Maciejowski J, de Lange T. Telomeres in cancer: tumour suppression and genome instability. Nat Rev Mol Cell Biol. 2017;18(3):175–86.
Article
CAS
PubMed
Google Scholar
Bolli N, et al. A DNA target-enrichment approach to detect mutations, copy number changes and immunoglobulin translocations in multiple myeloma. Blood Cancer J. 2016;6(9):e467.
Article
CAS
PubMed
PubMed Central
Google Scholar
Weinhold N, et al. Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma. Blood. 2016;128(13):1735–44.
Article
CAS
PubMed
PubMed Central
Google Scholar
Chng WJ, et al. Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: identification of 1p31-32 deletion as a prognostic factor in myeloma. Leukemia. 2010;24(4):833–42.
Article
CAS
PubMed
PubMed Central
Google Scholar
Walker BA, Morgan GJ. Use of single nucleotide polymorphism-based mapping arrays to detect copy number changes and loss of heterozygosity in multiple myeloma. Clin Lymphoma Myeloma. 2006;7(3):186–91.
Article
CAS
PubMed
Google Scholar
Jimenez C, et al. A next-generation sequencing strategy for evaluating the most common genetic abnormalities in multiple myeloma. J Mol Diagn. 2017;19(1):99–106.
Article
CAS
PubMed
Google Scholar
Kortum KM, et al. Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3) P) in -17p high risk disease. Br J Haematol. 2015;168(4):507–10.
Article
PubMed
Google Scholar
Ng PC, Henikoff S. Predicting deleterious amino acid substitutions. Genome Res. 2001;11(5):863–74.
Article
CAS
PubMed
PubMed Central
Google Scholar