Table 3 Genes located within common fragile sites according to the literature dataa, b, c, d
Fragile site | Chromosomal region | Start | End | Gene | Gene length |
|---|---|---|---|---|---|
Molecularly characterized fragile sites | |||||
FRA3B | 3p14.2 | 58 600 001 | 63 800 000 | FHITa | >1.5 Mbp |
FRA7H | 7q32.3 | 130 800 001 | 132 900 000 | /b | / |
FRA16D | 16q23.2 | 79 200 001 | 81 600 000 | WWOXc | 1.1 Mbp |
Not-characterized fragile sitesd | |||||
FRA1F | 1q21.2 | 147 500 001 | 150 600 000 | 33 genes | / |
FRA1N | 1p13.3 | 106 700 001 | 111 200 000 | 52 genes | / |
FRA2U | 2q35 | 214 500 001 | 220 700 000 | 70 genes | / |
FRA3C | 3q27.1 | 183 000 001 | 184 800 000 | 20 genes | / |
FRA3H | 3p21.31 | 44 200 001 | 50 600 000 | 78 genes | / |
FRA5K | 5q13.2 | 69 100 001 | 74 000 000 | 25 genes | / |
FRA5O | 5q33.2 | 153 300 001 | 156 300 000 | 8 genes | / |
FRA7F | 7q22.3 | 104 900 001 | 107 800 000 | 14 genes | / |
FRA11H | 11q13.4 | 70 500 001 | 75 500 000 | 48 genes | / |
FRA14G | 14q24.3 | 73 300 001 | 78 800 000 | 69 genes | / |
FRA16C | 16q22.1 | 66 600 001 | 70 800 000 | 95 genes | / |
FRA18B | 18q21.3 | 61 300 001 | 63 900 000 | 10 genes | / |