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Figure 1 | Molecular Cytogenetics

Figure 1

From: In silico molecular cytogenetics: a bioinformatic approach to prioritization of candidate genes and copy number variations for basic and clinical genome research

Figure 1

Outline of the basic procedure: molecular cytogenetic data (i.e. genes involved in a chromosome imbalance) is analyzed using epigenetic (gene expression) databases. According to epigenetic in silico analysis candidate genes are initially prioritized. Nextly, interactome analysis of proteins encoded by candidate genes is done. All these data is then fused for identification of disease candidate processes.

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