Fig. 3
From: Chromothripsis in lipoblastoma: second reported case with complex PLAG1 rearrangement
A Karyotype showing a 47,XY, + 8,der(8) × 2. B Metaphase FISH analysis with TelVysion 8p (green) and TelVysion 8q (orange) showing signals of 8p and 8q on the terminal ends of the short and the long arms on both abnormal der(8) chromosomes. C Metaphase FISH analysis with CEP8 (aqua) and MYC BA (green–red) probe showing all three signals present on both ends of the abnormal der(8) chromosomes. D FISH analysis on FFPE showing multiple copies of 3’ PLAG1 (centromeric-red), 5’PLAG1 (telomeric-green) and CEP8 (aqua). E Vertical CGH plot showing alternating 39 gains and 19 losses on chromosome 8. F Vertical plot of CGH with similar gains and losses. Blue denotes gain; Red denotes loss