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Table 4 Details of prenatal diagnosis results and pregnancy outcomes of 27 high-risk NIPT cases in the IVF group

From: Application of non-invasive prenatal testing to 91,280 spontaneous pregnancies and 3477 pregnancies conceived by in vitro fertilization

Patients

Maternal age (years)

Gestational age (weeks)

Pregnancy type

NIPT result

Prenatal diagnosis result

Clinical outcome

Case 1

37

16+5

Singleton

T13

46, XN

Delivery

Case 2

40

16+6

Singleton

T18

Abnormal ultrasound

Induced labour

Case 3

32

19+6

Singleton

T18

46, XN

Delivery

Case 4

34

19+3

Singleton

T21

47, XN + 21

Induced labour

Case 5

33

17+2

Singleton

T21

47, XN + 21

Induced labour

Case 6

38

17+2

Singleton

T21

47, XN + 21

Induced labour

Case 7

28

18+5

Twin

T21

47, XN + 21

Induced labour

Case 8

30

12+3

Singleton

T21

47, XN + 21

Induced labour

Case 9

32

15+5

Singleton

T21

46, XN

Delivery

Case 10

29

17+3

Singleton

T21

46, XN

Delivery

Case 11

43

15+5

Singleton

T21

Refuse prenatal diagnosis

Premature delivery

Case 12

32

15+6

Singleton

45, X

45, X

Induced labour

Case 13

36

17+1

Singleton

45, X

46, XN

Delivery

Case 14

32

16+5

Twin

45, X

46, XN

Delivery

Case 15

30

16+5

Singleton

45, X

46, XN

Delivery

Case 16

31

16+5

Singleton

45, X

Refuse prenatal diagnosis

Delivery

Case 17

31

20+0

Singleton

45, X

Refuse prenatal diagnosis

Delivery

Case 18

31

18+0

Singleton

47, XXX

46, XN

Delivery

Case 19

30

17+4

Singleton

47, XXX

46, [] [].14 ps+

Delivery

Case 20

24

17+3

Singleton

47, XXX

Refuse prenatal diagnosis

Loss to follow-up

Case 21

32

13+1

Singleton

47, XXX

Refuse prenatal diagnosis

Loss to follow-up

Case 22

27

14+3

Twin

47, XXX

Refuse prenatal diagnosis

Loss to follow-up

Case 23

30

18+1

Singleton

47, XXY

47, XXY

Induced labour

Case 24

39

13+0

Singleton

47, XXY

47, XXY

Delivery

Case 25

28

14+3

Singleton

47, XXY

47, XXY

Delivery

Case 26

28

16+3

Twin

47, XXY

46, XN

Delivery

Case 27

29

17+1

Twin

47, XYY

Refuse prenatal diagnosis

Delivery