Table 6 Comparison of findings with reports from South-East Asia
From: Cytogenetic profile of 1791 adult acute myeloid leukemia in India
Country | India | Japan | Japan | Singapore | China | China | Hong Kong | Korea | Malaysia | Malyasia |
|---|---|---|---|---|---|---|---|---|---|---|
Reference | This study | Nakase | Wakui | Enjeti | Cheng | Li | So | Byun | Meng | Ambayya |
Year | 2023 | 2000 | 2008 | 2002 | 2009 | 2012 | 2011 | 2016 | 2013 | 2021 |
Duration | 2003–17 | 1986–97 | 12/97–07/01 | 9/91–3/03 | 12/94–11/07 | 2003–10 | 89- 06/09 | 2007–11 | 2007–12 | 2012 -06/19 |
Type | Hosp | Hosp | AML-97# | Hosp | Hosp | Hosp | Hosp | Hosp | Hosp | Hosp |
No. of cases | 1791 | 494 | 809 | 501 | 1432 | 2516 | 834 | 2806 | 480 | 854 |
Karyotypes analysed | 1791 | 436 | 638 | 454 | 1293 | 2308 | 629 | 2717 | 480 | 601 |
Age, median (range) | 42 (18–85) | 51* (16–91) | 45 (15–66) | 48 (15–100) | 42 (4–84) | 37 (0.2–86) | 43 (0.3–70) | 50 (14–88) | 39 (0.3–81) | 45 (12–93) |
Male: Female ratio | 1.5:1 | 1.4:1 | 1.6:1 | 1.4:1 | 1.2:1 | 1.3:1 | 1.2:1 | 1.2:1 | 1:1 | 1.1:1 |
Normal | 36.1 | 43 | 42 | 39 | 42.3 | 39.8 | 39 | 42 | 70 | 49 |
Abnormal | 63.9 | 57 | 58 | 61 | 57.7 | 60.2 | 61 | 58 | 30 | 51 |
inv(3)/t(3;3) | 1.8 | NA | 0.8 | 0.7 | NA | 0.6 | 1 | 0.4 | NA | NA |
Del (5q)/minus 5 | 3.6/3.1 | 7.5*** | 0.3 | 6.6 | 0.8 | 0.3/1.4 | 4^^ | 3.4 | 0.8 | 5.3^^ |
t(6;9) | 0.9 | NA | 0.6 | 0.7 | NA | NA |  < 1 | 0.8 | NA | NA |
Minus 7/del (7q) | 6.8/2.5 | 7.5*** | 0.3 | 7 | 1.4 | 1.2/1.5 | 4^^ | 4.6 | 1.2 | 5.3^^ |
Plus 8 | 11.6 | 7.5*** | NA | 7.3 | 3.8 | 5.5 | 4 | 7.0 | 3 | 3.2 |
t(8;21) | 7.2 | 13.2 | 17.7 | 7.5 | 8.3 | 15.1 | 9 | 9.7 | 7.5 | 8.5 |
t(9;22) | 1.1 | NA | 1.1 | NA | 1.8 | 1.5 |  < 1 | NA | NA | NA |
t(9;11) | 0.8 | NA | 1.6 | 0.9 | NA | 0.3 | 1 | 0.8 | NA | NA |
Other/all^11q23 | 1.6 | 2.3^ | 3.4 | 1.3 | 1.2^ | 1.3 |  < 1 | 1.8 |  < 2^ | 2.5^ |
t(15;17) | 16.7 | 11.2 | NA | 11 | 14.3 | 16.7 | 16 | 10.7 | 2.3 | 14.3 |
inv(16)/t(16;16) | 1.7 | 2.7 | 4.1 | 1.1 | NA | 2.1 | 3 | 4.2 |  < 2## | 5 |
-17/abn 17p | 3.5/1.7 | NA | NA | NA | NA | 1.0/0.8 | NA | NA | NA | NA |
Plus 21 | 4.6 | NA | NA | NA | 1.6 | 2.4 | 1^^^ | NA | NA | NA |
Complex (≥ 3)/CK** | 15.6/11.2** | NA | 6.4## | 17 | 6.4 | 8.6 | 4^^^^ | 11.7 | 7.3** | NA |