Table 3 Myelodysplasia-related cytogenetic abnormalities

Patient details, n (%)`

All

208 (11.6)

65 (3.6)/4 (0.2)/1 (0.06)

122 (6.8)

45 (2.5)/5 (0.3)

14 (0.8)

15 (0.8)/16 (0.9)/3 (0.2)

26 (1.5)/9 (0.5)

63 (3.5)

10 (0.6)/17 (0.9)/4 (0.2

11 (0.6)/

11 (0.6)

M

121 (58)

41 (63)/3 (75)/0

82 (67)

31 (69)/2 (40)

9 (64)

10 (67)/11 (69)/2 (67)

19 (73)/4 (44)

47 (75)

7 (70)/9 (53)/4 (100)

6 (55)/

10 (91)

F

87 (42)

24 (37)/1 (25)/1 (100)

40 (33)

14 (31)/3 (60)

5 (36)

5 (33)/5 (31)/1 (33)

7 (27)/5 (56)

16 (25)

3 (30)/8 (47)/0

5 (45)/

1 (9)

Age

43 (18–76)

52 (19–82)/46 (25–61)/26

45 (18–74)

49 (21–72)/52 (31–55)

38 (19–78)

40 (19–57)/55 (26–78)/42 (20–72)

48 (21–82)/35 (19–63)

53 (18–82)

51 (32–70)/55 (20–73)/59.5 (55–70)

45 (18–65)

58 (25–77)

P value, age

Reference

0.002/0.82/0.38

0.29

0.04/0.75

0.51

0.1/0.41/0.15

0.45/0.41

0.01

0.08/0.09/0.02

0.85

0.12

Karyotype complexity

Single abn

67 (32.2)

10 (15.4)/0/0

30 (24.6)

11 (24.4)/0

0

2 (13.3)/0/1 (33.3)

0/0

3 (4.8)

4 (40)/0/1 (25)

1 (9.1)

1 (9.1)

Two abn

50 (24)

11 (6.9)/0/0

35 (28.7)

12 (26.7)/1 (20)

3 (21.4)

7 (46.7)/3 (18.8)/1 (33.3)

0/1 (11.1)

4 (6.3)

0/2 (11.8)/1 (25)

3 (27.3)/

6 (54.5)

 ≥ 3 abn

91 (43.8)

44 (67.7)/2 (50)/1 (100)

57 (46.7)

22 (48.9)/4 (80)

11 (78.6)

6 (40)/13 (81.3)/1 (33.3)

26 (100)/8 (88.9)

56 (89)

6 (60)/15 (88.2)/2 (50)

7 (63.6)

4 (36.4)

Association with RGA

Double

23 (11.1)

2 (3.1)/1 (25)/0

14 (11.5)

4 (8.9)

0

1 (6.7)/1 (6.3)/0

0/0

0

0/1 (5.9)/0

2 (18.2)

–

 ≥ 3

29 (13.9)

5 (7.7)/0/1 (100)

8 (6.6)

4 (8.9)/0

1 (7.1)

0/0/0

3 (11.5)/1 (11)

5 (7.9)

0/2 (11.8)/0

1 (9.1)

–

Plus 4

20

5/–/–

6

2/–

1

–

4/–

3

–/2/–

1

–

Minus 5

17

9/–/–

25

8/–

3

4/8/–

12/3

26

3/7/1

1

–

del 5q

12

–/–/–

15

5/1

2

1/5/1

5/3

13

2/6

2

–

add 5q

–

–

1

1/–

–

–

–

2

–

–

–

t 5q

1

–

–

–

–

–

–

–

–

–

–

Minus 7

18

15/1/–

–

6/–

2

3/4/1

14/–

16

3/2/

2

–

del 7q

10

5/1/–

6

–/–

3

–/3/–

3/–

7

–/2

1

–

t 7q

2

1/–/–

–

–

–

–

–

–

–/1/–

–

–

Plus 8

–

12/–/1

18

10/2

2

4/2/–

10/–

13

4/4

2

–

del 9q

6

6/–/–

4

5/–

1

2/1/–

–

3

1/–/–

–

–

del 11q

2

3/–/–

2

3/–

–

–/2/–

1/1

5

1/–

1

–

del 12p

4

1/–/–

3

–/–

–

–/2/–

1/–

–

1/–/–

–

–

add 12p

2

5/–/–

4

1/–

2

2/–/–

–/1

4

1/2/–

–

–

t 12p

–

1/–/–

1

1/–

–

–/–/–

–/–

–

–/1/–

–

–

Minus 13

10

5/–/–

14

3/–

1

1/–/–

–/–

1

1/1/–

–

–

del 13q

–

3/–/–

–

–/–

1

–/1/–

–/–

1

1/2/–

–

–

Minus 17

13

13/2/–

16

7/–

5

–/4/–

15/2

–

3/2/–

1

–

del 17p

4

2/–/–

3

–/–

1

1/1/–

1/1

3

–/–/–

–

–

add 17p

3

6/–/–

2

2/1

–

–/2/1

1/2

2

–/–/–

1

–

t 17p

1

1/–/–

1

1/–

–

–/–/–

–/–

–

–/–/–

–

–

i 17q

2

1/–/–

2

1/–

1

–

–/1

1

–/1/–

–

–

Minus 18

17

10/–/–

17

4/–

3

2/3/–

14/2

26

5/–

–

–

Plus 19

20

5/–/–

8

1/–

1

–/–/–

5/1

9

3/2/–

–

–

Plus 21

36

6/–/–

14

4/1

2

–/1/–

4/–

12

5/–

1

–

Plus 22

24

6/–/–

5

3/–

3

1/2/–

3/–

6

5/–

1

–

Minus X

10

1/–/1

5

1/–

2

1/1/–

4/–

4

1/3/–

–

–

Minus Y

3

4/–/1

5

1/–

1

–/1/–

3/–

8

2/1/–

–

–