Table 1 Overview of 1791 adult patients with AML

All patients

1791

42 (18–85)

1085 (60.6)

706 (39.4)

Karyotype details

Normal karyotype*

646 (36.1)

45 (18–85)

398 (36.7)

248 (35.1)

Abnormal karyotype

1145 (63.9)

40 (18–82)

687 (63.3)

458 (64.9)

Single abnormality

567 (31.7)

39 (18–76)

332 (30.6)

235 (33.3)

Two abnormalities

299 (16.7)

38 (18–75)

185 (17.1)

114 (16.1)

 ≥ 3 abnormalities

279 (15.6)

43 (18–82)

170 (9.5)

109 (6.1)

Complex karyotype (WHO/ICC)**

200 (11.2)

48 (18–82)

131 (7.3)

69 (3.9)

Complex karyotype (ELN)***

184 (10.3)

42 (21–82)

126 (7)

58 (3.2)

Monosomal karyotype

158 (8.8)

48.5 (21–82)

110 (6.1)

48 (2.7)

Types of abnormalities

RGA

585 (32.7)

35 (18–72)

330 (18.4)

255 (14.2)

MRC

403 (22.5)

46 (18–82)

262 (14.6)

141 (7.9)

Other^ abnormalities

157 (8.8)

42 (18–74)

95 (5.3)

62 (3.5)

AML-NOS (other^, and normal*)

803 (44.8)

44 (18–85)

493 (27.5)

310 (17.3)

Moorman classification

Translocations

606 (33.8)

36 (18–76)

341 (19)

265 (14.8)

Deletions

323 (18)

46.5 (18–85)

217 (12.1)

106 (5.9)

Trisomies

216 (12.1)

43 (18–76)

129 (7.2)

87 (4.9)

Blood counts

WBC count × 10⁹/L, n = 1759

7.1 (0.2–824)

7.1 (0.2–821.4)

7.1 (0.3–824)

Haemoglobin, g/dl, n = 1758

8.1 (2.1–18.6)

8.1 (2.3–18.6)

8 (2.1–15.6)

Platelet count × 10⁹/L, n = 1759

37 (2–1541)

38 (2–690)

36 (3–1541)