Fig. 3
From: Cytogenetic profile of 1791 adult acute myeloid leukemia in India
A. Karyotype: 46,XY,t(15;17)(q24;q21). B. FISH: dual colour, dual fusion probe for chromosome 15 (PML, red) and chromosome 17 (RARA, green). Arrows show fusion signals on both derivative chromosomes. C. Karyotype: 46,XX,+8, inv (16)(p13.1q22). D. FISH, dual colour break-apart rearrangement probe for chromosome 16q22.1 (CBFB). Fusion signal on normal chromosome 16 (red, 5’CBFB; green, 3’CBFB). Arrow shows the derivative chromosome 16 with separate red and green signals. Karyotypes are G-banded. FISH from Abbott Molecular, Des Plaines, IL, USA)