Fig. 4From: BCR::ABL1-like acute lymphoblastic leukaemia: a single institution experience on identification of potentially therapeutic targetable casesThe high resolution melt analysis (HRMA)—top field, and Sanger sequencing result (bottom field) in the CRLF2-r patients. HRMA revealed abnormal melting profile in one studied sample, in contrast to the normal double-stranded DNA dissociation characteristics during heating in control samples (wild type, WT). In the presented case, Sanger sequencing study revealed the presence of the variant LRG_612:c.2049A>C(p.Arg683Ser). Reference transcript ID (RefSeq): NM_004972.4:c.2049A>C, NP_004963.1:p.(Arg683Ser)Back to article page