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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: A treatment-refractory aggressive MDS-MLD with multiple highly complex chromosome 5 intrachromosomal rearrangements: a case report

Fig. 2

Bone marrow interphase and metaphase FISH. A 5q deletion probe (Abbott Molecular): a single red signal indicating a 5q31 (EGR1) deletion and two normal control 5p15.2 (D5S23/D5S721, green) signals. B Whole-chromosome 5 paint probe (Abbott Molecular, red) on bone marrow metaphase preparations showing intense hybridization to both the normal and derivative 5, with no hybridization to any other chromosome. C Hybridization with 5q32 PDGFRB break apart probe (Cytocell) showing deletion of the centromeric side of the PDGFRB probe (red), while the telomeric side (green) appears intact. D PDGFRB probe map (adapted from ogt.com)

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Molecular Cytogenetics

ISSN: 1755-8166