Fig. 2
From: Molecular combing and its application in clinical settings
MCT result using the probe RP11-71J12 in 13q14.13 (GRCh37/ hg19; chr13:46,439,690–46,587,782) labeled in SpectrumOrange and hybridized to DNA fibers spread on homemade silanized coverslips [56]. DNA-fibers were stained by YOYO-1 (green). Picture was acquired on a Zeiss Axioplan microscope (Jena, Germany) using ISIS software (Metasystems, Altlussheim, Germany). The DNA fibers were produced using FiberComb – Molecular Combing System (Genomic Vision, Bagneux, France)