Skip to main content

Table 1 Based on a literature review (Additional file 1: Table S1) here numbers of NIPT-positive cases tested for the five indications trisomy 13, 18 and 21, SCAs and RATs are given together with false-positive and false-negative case-numbers

From: False-positives and false-negatives in non-invasive prenatal testing (NIPT): what can we learn from a meta-analyses on > 750,000 tests?

Indication

Tested overall

+91.63% of overall tested

Positive tested and checked

False positive

False negative

a

all 5 indications tested

41,472

38,001

460+

217

3

b

T13

721,157

639,378

687

304

13

T18

730,253

647,442

1447

268

30

T21

752,979

667,591

5283

517

31

SCAs

300,894

266,773

1192

661

1

RATs

158,395

140,433

342

289

0

all

n.a.

n.a.

8951*

2039

75

  1. *All positive tested = 10,096 = 1.314%; +checked positive NIPT cases: 88.66%
Back to article page

Molecular Cytogenetics

ISSN: 1755-8166