Table 1 The efficiency of NIPT in screening T21, T18, T13
From: Clinical application of noninvasive prenatal testing in the detection of fetal chromosomal diseases
NIPT results | Positive cases (N) | Amniotic fluid puncture Cases (N) | TP (N) | FP (N) | FN (N) | TN (N) | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | FPR (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|
T21 | 48 | 48 | 44 | 4 | 0 | 25454 | 100 | 99.98 | 91.67 | 100 | 0.02 |
T18 | 15 | 11 | 5 | 6 | 0 | 25491 | 100 | 99.98 | 45.45 | 100 | 0.02 |
T13 | 8 | 6 | 2 | 4 | 0 | 25496 | 100 | 99.98 | 33.33 | 100 | 0.02 |