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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: Complex rearrangement in acute myeloid leukemia M2 with RUNX1/RUNX1T1 fusion involving chromosomes 8, 17 and 21

Fig. 1

Morphologic and cytogenetic profile. a Bone marrow smear aspirate show blast. b Partial metaphase spread of G-banded chromosomes. A three way translocation t(8;21;17) at bands 8q22, 21q22 and 17p13 which would be consistent with AML. c FISH with the AML1/ETO dual color, dual-fusion probe. The figures depicts the RUNX1/RUNX1T1 fusion on chromosome 17. d FISH with whole-chromosome painting (WCP) for chromosomes 8, 17 and 21. A multi-color banding specific for chromosome 8 and 17, showing the origin and the breakpoints of each rearrangement

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Molecular Cytogenetics

ISSN: 1755-8166