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Table 3 Copy number alterations associated with molecular subtypes of human BC, according to [32], with the copy number variants (CNVs) in cell lines JC

From: Cytogenomic characteristics of murine breast cancer cell line JC

DNA changes
In BC subtypes Human BC JC
HER2+/ERBB2   
17q11.1~12 gain no CNV
17q21.31~23.2 gain gain but ERBB2 is not included
SUM of concordance 0/2
Basal-like tumors   
 4p15.31 loss loss
 5q12.3~13.2 loss gain
 5q33.1 loss loss
 6p12.3 gain no CNV
 6p21.1~23 gain gain
 8q24.21~24.22 gain gain
 10p12.33~14 gain loss
 10q23.33 loss loss
 12q13.13 loss gain
 12q13.3 loss loss
 15q15.1 loss no CNV
 15q21.1 loss no CNV
SUM of concordance 6/12
Luminal A   
 1q21.3 gain no CNV
 1q44 gain loss
 16p13.13 gain no CNV
 16p13.12 gain loss
 16q11.2~13 loss no CNV
 16q22.1-24.1 loss no CNV
SUM of concordance 0/6
Luminal B   
 1p31.3 loss loss
 8p21.2 loss loss
 17q23.2 gain loss
SUM of concordance 2/3
  1. Concordances with human CNVs are highlighted in bold
  2. CNV copy number variant