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Table 3 Veracity clinical Performance

From: Non-invasive prenatal testing of fetal chromosomal aneuploidies: validation and clinical performance of the veracity test

NIPT result for aneuploidies (T21, T18, T13) Number Follow-up Correct Specificity NPV
Normal 10280 10280 10280 99.98% (95% CI, 99.93–99.998%) 100% (95% CI, 99.96–100%)
NIPT result for aneuploidies (T21, T18, T13) Number Follow-up Correct Sensitivity PPV
Trisomy 21 126 44 44 100% (95% CI, 92–100%) 100% (95% CI, 92–100%)
Trisomy 18 24 10 10 100% (95% CI, 69–100%) 100% (95% CI, 69–100%)
Trisomy 13 16 7 5 100% (95% CI, 48–100%) 71% (95% CI, 29–96%)
NIPT result for SCAs Number Follow-up Correct Specificity NPV
Normal 6200 6200 6200 99.95% (95% CI, 99.86–99.99%) 100% (95% CI, 99.94–100%)
NIPT result for SCAs Number Follow-up Correct Sensitivity PPV
Monosomy Χ 16 7 4 100% (95% CI, 40–100%) 57% (95% CI, 18–90%)
Trisomy X 6 2 2
47, ΧΧΥ 10 4 4
47, ΧΥΥ 3 0
48, ΧXYY 1 1 1