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Table 2 NIPT results for RCAs on two NGS platforms

From: Non-invasive prenatal testing to detect chromosome aneuploidies in 57,204 pregnancies

RCAs Illumina Proton Total
NIP AM TP PPV (%) NIP AM TP PPV (%) NIP AM TP PPV (%)
7 15 5 0 0.00 10 4 0 0.00 25 9 0 0.00
2 6 1 0 0.00 5 3 0 0.00 11 4 0 0.00
16 4 2 / 0.00 3 2 0 0.00 7 4 / 0.00
3 2 1 0 0.00 6 4 0 0.00 8 5 0 0.00
22 1 1 0 0.00 7 3 1 33.33 8 4 1 25.00
8 2 / / / 4 3 0 0.00 6 3 0 0.00
5 1 1 0 0.00 3 2 0 0.00 4 3 0 0.00
10 3 1 0 0.00 1 / / / 4 1 0 0.00
14 3 2 0 0.00 1 1 0 0.00 4 3 0 0.00
20 1 1 0 0.00 3 2 0 0.00 4 3 0 0.00
1 2 2 0 0.00 / / / / 2 2 0 0.00
9 1 / / / 1 / / / 2 / / /
11 2 1 0 0.00 / / / / 2 1 0 0.00
15 2 / / / / / / / 2 / / /
19 1 / / / 1 / / / 2 / / /
4 / / / / 1 1 0 / 1 / / /
  1. AM amniocentesis, NIP NIPT positive, PPV positive predictive value, RCA rare chromosome aneuploidy, TP true positive