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Table 1 Distributions of maternal age and gestational age of pregnant women who underwent NIPT on two NGS platforms

From: Non-invasive prenatal testing to detect chromosome aneuploidies in 57,204 pregnancies

 

Illumina

Proton

MA (years)

 Median

30.0

30.0

 Mean ± SD

30.1 ± 5.0

30.4 ± 5.0

 Min-Max

16–50

15–49

AA (≥35)

8265 (22.1%)

5021 (25.3%)

 AA with positive NIPT

158 (1.9%)

88 (1.8%)

GA (weeks)

 Median

18.0

17.0

 Mean ± SD

17.7 ± 2.0

17.6 ± 2.1

 Min-Max

11–30

11–30

Twin pregnancies

207 (0.6%)

218 (1.1%)

IVF-ET pregnancies

457 (1.2%)

429 (2.2%)

  1. AA Advanced age, GA gestational age, MA maternal age, NGS next-generation sequencing