Fig. 2

Overlap map of 10q21.3q22 deletions. The deletion identified in our patient is the second largest reported deletion in this region that has been characterized by chromosomal microarray. Comparison of the reported deletions reveals a 754 kb overlapping deleted region (gray) that is shared by eight of the ten patients. Dashed gray lines represent the breakpoints of patient 50 in Bartnik et al. (2014) [9]. The CTNNA3 open reading frame is boxed in. Note: Patients characterized by G-banded chromosome analysis are not depicted in this figure due to the uncertainty of the deleted region