Table 3 Chromosome copy numbers of five karyotypes (K) of mouse hybridomas Hyb H12, Hyb F3, Hyb 94 and Hyb 1-5
From: Is cancer progression caused by gradual or simultaneous acquisitions of new chromosomes?
Clone | Hybridoma H12 | Hybridoma F3 | Hybridoma 94 | Hybridoma 1-5 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Karyotypes | K1 | K2 | K3 | K4 | K5 | K1 | K2 | K3 | K4 | K5 | K1 | K2 | K3 | K4 | K5 | K1 | K2 | K3 | K4 | K5 |
Chromosome Copy # | 71 | 70 | 71 | 68 | 75 | 77 | 78 | 80 | 81 | 81 | 71 | 77 | 71 | 71 | 82 | 107 | 105 | 93 | 89 | 99 |
Chromosomes | ||||||||||||||||||||
1 | 2 | 2 | 2 | 1 | 2 | 3 | 3 | 3 | 3 | 3 | 1 | 1 | 1 | 2 | 1 | 2 | 3 | 2 | 3 | 2 |
2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 3 | 3 | 3 | 4 | 3 | 4 | 3 | 3 | 3 | 4 | 3 | 4 |
3 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 |
4 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 2 | 1 | 2 |
5 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 2 | 0 | 2 | 4 | 3 | 3 | 2 | 3 |
6 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 3 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 |
7 | 1 | 2 | 2 | 1 | 2 | 1 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 3 | 1 | 4 | 2 | 2 | 2 |
8 | 1 | 1 | 1 | 1 | 2 | 3 | 3 | 2 | 3 | 3 | 3 | 3 | 2 | 1 | 2 | 3 | 3 | 1 | 2 | 2 |
9 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 2 | 2 | 3 | 5 | 3 | 2 | 1 | 4 |
10 | 1 | 1 | 1 | 1 | 1 | 3 | 3 | 3 | 2 | 3 | 2 | 2 | 3 | 3 | 3 | 2 | 2 | 1 | 2 | 1 |
11 | 3 | 3 | 3 | 3 | 3 | 4 | 4 | 3 | 5 | 4 | 3 | 1 | 1 | 3 | 3 | 6 | 3 | 4 | 4 | 4 |
12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 1 | 2 | 2 | 2 | 2 |
13 | 3 | 3 | 3 | 2 | 4 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 2 | 1 | 2 | 2 | 1 | 3 | 1 | 3 |
14 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 2 | 3 | 3 | 4 | 2 | 3 | 3 | 4 | 5 | 4 | 5 | 4 |
15 | 3 | 3 | 3 | 3 | 3 | 4 | 4 | 4 | 4 | 4 | 4 | 2 | 2 | 5 | 4 | 4 | 4 | 4 | 4 | 3 |
16 | 2 | 2 | 2 | 2 | 3 | 2 | 3 | 3 | 3 | 3 | 3 | 2 | 2 | 2 | 3 | 2 | 3 | 3 | 4 | 1 |
17 | 1 | 1 | 1 | 1 | 1 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 2 | 2 | 2 | 1 | 2 | 2 | 1 | 2 |
18 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 0 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 |
19 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 2 | 3 | 2 | 3 | 3 |
X | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 0 | 2 | 2 | 2 | 2 | 1 | 1 | 3 |
Y | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
der(X;10) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 2 | 2 | 2 |
der(2;X) | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2 | 2 | 1 |
der(X;18) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 |
der(19;X) | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 |
der(8;1) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 3 | 1 | 1 | 1 |
der(13;1) | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 |
der(2;3;1) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 1 | 1 | 1 | 2 |
der(1;3;7) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 0 | 1 | 1 | 2 | 2 | 1 | 2 |
der(1;11) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 1 |
der(17;1) | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 2 | 2 | 2 | 0 | 2 |
der(2;6) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 2 | 2 | 2 | 1 | 1 |
der(2) | 2 | 2 | 2 | 2 | 0 | 1 | 2 | 1 | 1 | 1 | 2 | 2 | 2 | 3 | 0 | 4 | 0 | 1 | 2 | 2 |
der(3;6) | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 1 |
der(3;4) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 |
der(4;3) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 |
der(4;5) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
der(5;4) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 2 | 2 | 2 | 1 | 3 | 1 |
der(12;5) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 1 | 1 |
der(6;5) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 |
der(17;6) | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 0 | 1 | 2 | 2 | 2 | 1 | 2 |
der(6;18;13) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 2 | 2 | 1 | 2 | 2 |
der(11;6) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 |
der(7) | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 1 | 1 |
der(8;14) | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
der(9;14) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 1 | 2 |
der(12;10) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 2 | 1 | 2 | 1 | 2 |
der(12;17) | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 4 | 3 |
der(14;8;1;13) | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 1 | 1 |
der(15) | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 4 | 4 | 2 | 4 | 3 |
der(16) | 2 | 2 | 2 | 2 | 2 | 2 | 0 | 2 | 3 | 3 | 2 | 2 | 2 | 1 | 2 | 4 | 4 | 1 | 1 | 1 |
der(18;15) | 2 | 2 | 2 | 2 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 1 | 2 | 1 |
der(X;1) | 0 | 0 | 0 | 1 | 1 | |||||||||||||||
der(X;2;X;2?) | 1 | 1 | 1 | 0 | 1 | |||||||||||||||
mar(11;6) | 1 | 1 | 1 | 1 | 1 | |||||||||||||||
mar(1;11) | 1 | 1 | 1 | 1 | 1 | |||||||||||||||
Non-Clonal Markers | 1 | 1 | 1 | 0 | 2 | 0 | 0 | 3 | 2 | 0 | 1 | 1 | 6 | 0 | 4 | 0 | 1 | 3 | 0 | 3 |