From: Is cancer progression caused by gradual or simultaneous acquisitions of new chromosomes?
Myeloma and Hybridoma clones | Clonal chromosome number ± SD | Gains of chromosomes compared to the 52 of myeloma | Gains / losses of chromosomes compared to the 92 of a theoretical myeloma-B-cell hybrid |
---|---|---|---|
Mouse | 40 | – | – |
Myeloma Ag8 | 52 ± 1 | – | – |
Hyb CN-13 ab+ | 85 ± 2 | 33 | - 7 |
Hyb cl-12 ab+ | 86 ± 9 | 34 | - 6 |
Hyb cl-9 ab+ | 105 ± 11 | 53 | + 13 |
Hyb H12 ab- | 71 ± 2.5 | 19 | - 21 |
Hyb F3 ab- | 79 ± 2 | 27 | - 13 |
Hyb 94 | 74 ± 5 | 22 | - 18 |
Hyb 1-5 | 99 ± 7.5 | 47 | + 7 |