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Fig. 4 | Molecular Cytogenetics

Fig. 4

From: Noninvasive prenatal diagnosis of fetal aneuploidy by circulating fetal nucleated red blood cells and extravillous trophoblasts using silicon-based nanostructured microfluidics

Fig. 4

Fluorescent in situ hybridization (FISH) for the captured fnRBC from 3 pregnant women with an aneuploid fetus of a trisomy 13, b trisomy 18, and c trisomy 21. In a and c, chromosome 13 was identified by a panel of probes (RB1, D13S1195, D13S1155, D13S915) in green and chromosome 21 was identified by a panel of probes (D21S270, D21S1867, D21S337, D21S1425, D21S1444, D21S341) in orange. In b, chromosome 18 was identified by a probe (D18Z1) in aqua and chromosome X was identified by a probe (DXZ1) in green

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