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Table 3 Cytogenetics of patients in each WHO category

From: Clinicohematological and cytogenetic profile of myelodysplastic syndromes in Pakistan-compare and contrast

 

Total No. of cytogenetic performed N = 98

Normal karyotype N = 54

Abnormal karyotype N = 44

Chromosomal Abnormalities (N)

WHO subtype:

(%)

(%)

(%)

 

RCMD

22.4

10.2

12.2

t(6;9) (p23;q23) (1)

Del(20q) (2)

+ 8 (1)

−7 (4)

46,XY,+3,del(5q),del(10q) (1)

48,XY,del(5q),+8 + 11,del (20q) (1)

47,XY,del(5q),+8,del(20q) (1)

49,XY,del(5q),del(7q),+8 + 11 + 17,del(20q) (1)

RAEB II

27.5

13.2

14.20

Del(9q) (1),del(5q) (1), del(7q) (2), del(20q) (2)

+ 8 (1)

−7 (1),−8 (1),−11 (1)

45,XY,t(6;9) (P23;q34),−3,+17 (1)

46,XY,t(1;9), del(9q),+11 (1) 47,XY,del(5q), +8 del(20q) (1)

49,XY,del(5q),del(7q),+8,del(11q),+17,del(20q) (1)

RAEB-I

16.32

7.14

9.1

Del(9q) (1), Del(20q) (1)

+8 (1)

−7 (2),−7,8 (1)

45,XY,del(5q),del(7q),-Y (1)

47,XX,t(3;12) (q26.2;q22),del(7q),+15 (1)

47,XY,+11 + 17,−22 (1)

Hypoplastic MDS

11.2

9.1

2.04

+8 with del(7q) (1)

+12 (1)

RA

7.14

6.12

1.02

47,XY,+11,+17,del(20q) (1)

RCUD

5.1

4.08

1.02

t(1;9) (q11;q34) along with del(9q) (1)

RARS

2.04

2.04

 

RCMD-RS

2.04

2.04

 

MDS with 5q

5.10

 

5.10

Del5q (5)

RCC

1.02

1.02