Table 3 Clinical outcomes of patients undergoing NGS and aCGH

Number of patients undergoing PGS

135

202

—

Number of embryos diagnose by PGS^a

472

827

—

 Euploid

180 (38.1%)

364 (44.0%)

0.04*

 Aneuploid

219 (46.4%)

370 (44.7%)

0.60

 Mosaic

25 (5.3%)

14 (1.7%)

<0.01**

 Segmental aneuploid

48 (10.2%)

79 (9.6%)

0.77

Number of patients with no euploid embryo to transfer^a

44 (32.6%)

42 (20.8%)

0.02*

 Aneuploid

23 (17.0%)

32 (15.8%)

0.77

 Mosaic

6 (4.4%)

0 (0%)

—

 Segmental aneuploid

15 (11.1%)

10 (5.0%)

0.05

Number of transferred patients^a

90 (66.7%)

129 (63.9%)

—

Mean female age (years)^b

37.5 ± 5.5

(27–53)

37.2 ± 4.5

(27–51)

0.68

 Severe male factor

9 (10%)

25 (19%)

0.08

 Advanced female age (≥36 years)

32 (36%)

42 (33%)

 Repeated implantation failure

32 (36%)

47 (36%)

 Oocyte –donation cycle for SET

17 (19%)

15 (12%)

Baseline AMH (ng/mL)^b

4.5 ± 3.7

4.9 ± 3.6

0.42

Antral follicle count^b

11.0 ± 4.6

11.2 ± 4.7

0.82

Mean endometrial thickness (mm)^b

9.3 ± 1.8

9.2 ± 1.4

0.72

 HCG(+) pregnancy

66 (73%)

78 (60%)

0.048*

 Implantation

64 (53%)

67 (45%)

0.043*

 Clinical pregnancy

59 (66%)

73 (57%)

0.18

 Ongoing pregnancy

51 (57%)

59 (46%)

0.11

 Multiple pregnancy

3 (3%)

4 (3%)

1.00

 Miscarriage

8 (9%)

14 (11%)

0.48

Average transferred embryo per cryotransfer^b

1.2 ± 0.5

1.2 ± 0.4

0.11