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Fig. 1 | Molecular Cytogenetics

Fig. 1

From: Identification of mosaic and segmental aneuploidies by next-generation sequencing in preimplantation genetic screening can improve clinical outcomes compared to array-comparative genomic hybridization

Fig. 1

Examples of inconsistent aneuploidy between the two chromosome screening platforms generated by the same amplification products. NGS, next-generation sequencing; aCGH, array-comparative genomic hybridization. a Embryo 5C was identified as aneuploid with trisomy 18 and duplication of ch.7p23.3-p21.2 using the NGS platform, but the aneuploidy was suspected as mosaicism at ch.18 using the aCGH platform. b Embryo 12C was identified as aneuploid with duplication of ch.7 q31.1-q36.3 using the NGS platform (47 Mbp), but the aneuploidy was not obvious with the aCGH platform. Embryo 3C was identified as aneuploid with duplication of ch.9q12-q34.3 using the NGS platform (83 Mbp), but the aneuploidy was suspected as mosaicism with the aCGH platform

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