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Fig. 3 | Molecular Cytogenetics

Fig. 3

From: Identification of small marker chromosomes using microarray comparative genomic hybridization and multicolor fluorescent in situ hybridization

Fig. 3

Identification of the chromosomal origin of the sSMC(15) by FISH and array CGH. a FISH analysis using D15Z1 (15p11.2; spectrum red) probe shows a red hybridization signal on the marker chromosome (case 3); b-c FISH analysis of the idic(15) using D15Z1 (15p11.2; spectrum green) and D15S11 (15q11-q13; spectrum red). sSMCs have two green hybridization signals of D15Z1 with no D15S11 signal (case 3, B; case 4, C); d SMC(15) identified with M-FISH 15 (case 4); e Array CGH analysis results showing amplification from 15q11.1 to 15q13.1 (chr15: 20,102,541-28,525,460), spanning 8.4 Mb (case 5)

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Molecular Cytogenetics

ISSN: 1755-8166