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Fig. 4 | Molecular Cytogenetics

Fig. 4

From: Rare double-hit with two translocations involving IGH both, with BCL2 and BCL3, in a monoclonal B-cell lymphoma/leukemia

Fig. 4

Schematic representation of the rearrangements described in clone 1 and clone 2. Chromosomes involved in rearrangements are shown on the right. a Rearrangements in clone 1 involving IGH (14q32) and BCL3 (19q13.1) which results in two derivative chromosomes (der(19) and der(14). Rearranged chromosomes 14 and 19 are indicated by an arrow on the right. b Rearrangements in clone 2 which includes chromosome duplication event and IGH (14q32) and BCL2 (18q21) translocation in addition to IGH;BCL3 rearrangements. Therefore clone 2 contains 8 derivative chromosomes (a pair of each der(19), der(18), der(14)t(14;19), and der(14)t(14;18)). Rearranged chromosomes 18 and 19 are indicated by the arrows on the right

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Molecular Cytogenetics

ISSN: 1755-8166