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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Rare double-hit with two translocations involving IGH both, with BCL2 and BCL3, in a monoclonal B-cell lymphoma/leukemia

Fig. 2

a Karyotype of the first clone. The first clone (stemline [sl]), six cells, contained a translocation between the long (q) arms of chromosomes 14 and 19 (arrows), and gain of one copy of chromosome 12 (underlined). b BCL3 break-apart FISH probe (green/red) indicates rearrangement of a BCL3 locus in the first clone (arrows). Normal FISH signal is shown on the right side of the panel for comparison. c IGH break-apart FISH probe (green/red) indicates rearrangement of an IGH locus in the first clone (arrows). Normal FISH signal is shown on the right side of the panel for comparison

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Molecular Cytogenetics

ISSN: 1755-8166