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Fig. 2 | Molecular Cytogenetics

Fig. 2

From: Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression

Fig. 2

Karyotype from patient 3 showing a 45,XX,inv(3)(q21q26.2)x2,-7 and b a metaphase FISH study using EVI1(MECOM) showing breakapart of green and red signals on both chromosome 3. ACGH + SNP analysis of patient 3 showed no apparent evidence of CN-LOH on chromosome 3q (c) and a very low level of monosomy 7 with a black line slightly below the zero line (d)

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Molecular Cytogenetics

ISSN: 1755-8166