Fig. 2
From: Assessment of copy number variations in the brain genome of schizophrenia patients
Gene dosage evaluation of the individual positive pairs in CGH analysis. DNA was prepared from the striatum and prefrontal cortex of the same subjects whose pairs resulted in the exclusive penetrance calls in array CGH analysis (Selection 1). DNA was then subjected to qPCR using the RNase P gene as an internal control in quadruplicate. Moreover, to compare the gene dosage between the striatum and prefrontal cortex, ratios of DNA dosages of the schizophrenia patients to those of the control subjects were calculated in each brain region and plotted. Statistical comparisons of gene dosages or their ratios were conducted by two-way ANOVA with the subject factors of disease and sample pair, considering technical deviations. *p < 0.05, **p < 0.01, ***p < 0.001