Table 1 In situ hybridization, microarray and cytogenetic data of the patients

1

4902

M

63

RCMD

no

not done

del(16)(q11q23)

46,XY,del(16)(q11q23)[4]/46,XY[6]

4519

F

59

AML

no

loss 7 (44%)

del(3)(p24p22),del(3)(p14p12),del(4)(p15),dup(5)(p11),del(5)(q11q35),del(7)(p14p11), del (7)(q11q26),del(10) (q11q24),del(10)(q25q26),dup(22)(q11)

45,XX,del(5)(q13q33),-7[4]/46,XX[16]

4898

F

42

RCMD

no

loss 7 (50%)

−7,+21,+22

45,XX,-7[4]/47,sl,+21,+22[5]/46,XX[1]

4893

M

80

RAEB-1

no

trisomy 8 (50%)

+8

47,XY,+8[10]

4895

F

59

RCMD-RS

no

trisomy 8 (23%)

+8

47,XX,+8[6]/46,XX[4]

4896

M

72

RCMD

no

loss 8 (47%) loss 7 (50%)

del(5)(q21q31),-7

44,XY,del(5)(q15q33),-7,dic(15;17)(p11;p11),-18,der(21;22)(q10;q10),+2mar[cp8]/46,XY[2]

4912

M

64

RAEB-2

no

not done

+8,+21

47,XY,+21[1]/48,sl,+8[9]

2

4522

M

57

RCMD

grade 3

loss 20q (32%) trisomy 8 (18%)

del(3)(p24q25),del(5)(q14q34),del(6)(p24q16), del(7)(q11q32),+8,del (20)(q11)

40~44,XY,-5,-6,-7,+8,-20,+4mar[cp7]/46,XY[3]

4894

M

67

RCMD

grade 2

loss 20q (77%)

del(20)(q11q13)

46,XY,del(20)(q13)[10]

4899

M

58

RAEB

grade 3

not done

del(2)(p23),del(4)(p12),del(4)(q12q13.2), del(5)(q14q35),del(7) (q21q36),del(12)(p12p13),del(20)(q11q13)

44~47,XY,-2,-2,-4,del(4)(q31),-5,-7,add(9)(q34),add(12)(p13),−13,-15,-16,-17,add(17)(p13),del(20)(q11),+3~7mar[cp8]/46,XY[2]

4903

M

58

AML

patchy fibrosis

faillure

no CNA

44~47,XY,-2,-2,-4,-4,+6,-7,-9,-10,-13,-13,-17,add(17)(p13),−19,del(20)(q11),+21,+21,+4~8mar[cp8]/46,XY[2]

4523

F

58

RAEB-2

grade 3

loss 7 (46%) loss 5 (29%)

del(5)(q14q33),-7

45,XX,t(4;17;20)(q31;q12;q13),del(5)(q13q33),-7[10]

4520

M

70

RAEB-2

grade 3

loss 7 (61%) loss 5 (40%)

-Y,del(5)(q11q34),-7,del(17)(p13),-18

42~44,X,-Y,-5,-7,+?12,-13,add(17)(p13),-20,-21,+3mar[cp13]

4521

F

59

RCMD

grade 2

loss 5q (19%)

del(4)(q24q26),del(5)(q13q35),del(6)(q11q21), del(7)(q11),del (17)(p13.1p13.3)

45~46,XX,add(1)(q32),del(5)(q?22q33),del(6)(p22),add(7)(q11),-10,-13,del(17)(p11),+2~3mar[cp10]

3

4904

F

60

RAEB-2

no

not done

no CNA

46,XX[20]

4906

F

64

vit. B12 deficiency

no

not done

no CNA

46,XX[23]

4897

M

71

hypoplastic AML

no

not done

no CNA

46,XY[20]

4518

F

45

pure red cell aplasia

no

loss 7q (34%)

no CNA

46,XX[20]

4890

M

58

RCMD

no

not done

no CNA

46,XY[20]

4892

F

63

RCMD-RS

no

not done

no CNA

46,XX,t(3;3)(q21;q26)[11]

4900

F

63

RAEB-1

no

not done

no CNA

46,XX[20]