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Figure 3 | Molecular Cytogenetics

Figure 3

From: Pediatric donor cell leukemia after allogeneic hematopoietic stem cell transplantation in AML patient from related donor

Figure 3

Interphase FISH studies. a) XY probe (X spectrum green and Y spectrum red) shows the presence of donor female cells. b) CEP 10 (spectrum green) probe supports the trisomy of chromosome 10. c) No disruption of MLL gene was observed using a MLL break apart probe; the third signal corresponds to the extra chromosome 11. d) Simultaneous p53 (spectrum green) and ATM (spectrum Orange) test, showed no deletion of any suppressor gene, but the third signal of ATM agrees with the trisomy 11. e) Tel-AML1 (red/green signal) evaluation was negative for the presence of the fusion gene.

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Molecular Cytogenetics

ISSN: 1755-8166