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Figure 3 | Molecular Cytogenetics

Figure 3

From: Hyperdiploidy associated with T315I mutation in BCR-ABL kinase domain in an accelerated phase-chronic myeloid leukemia case

Figure 3

ASO-PCR monitoring and corresponding sensitivity test for detected T315I mutation pre-IM treatment. ASO-PCR products on genomic DNA obtained from healthy donor and our patient. Line M, 1 kb DNA ladder; lines 1,2 blank; lines 3–10 patients ASO-PCR T315I wild-type primers; P, our patient; lines 11–18 ASO-PCR T315I mutated primers; and P*, our patient with T315I mutation.

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