Figure 2
From: On the significance of germline cytogenetic rearrangements at MYCN locus in neuroblastoma
Dosage of genes located within the MYCN amplicon. Tumor - somatic (NB tumor) DNA of the patient. Blood - constitutional (peripheral blood leukocytes) DNA of the NB patient. Control - constitutional (peripheral blood leukocytes) of the control patient with constitutional partial 2p duplication but no NB. X-axis chromosomal coordinates and gene locations are presented according to NCBI36/hg18; Y-axis shows DNA ploidy. Genomic positions of the FRA2C fragile sites are given as established by Blumirch et al. [21].