Figure 2
From: Characterization of a case of follicular lymphoma transformed into B-lymphoblastic leukemia
Microarray and FISH findings of transformed follicular lymphoma. Copy losses (blue) and copy gains (pink) for oligonucleotide array-based cooperative genomic hybridization (aCGH) are shown for chromosomes (A) 8, (B) 14, and (C) 18. Note that the zero value for Log2 ratio is reflective of a triploid (3n) genotype (confirmed by karyotypes and FISH), as aCGH cannot discern autosomal ploidy. FISH using indicated BAC probes illustrate (D) co-localization of MYC and BCL2 on a marker chromosome, and (E) co-localization of these genes with IGH on the same marker. Probe colors match the indicated probe names.