Figure 3
From: Pure 16q21q22.1 deletion in a complex rearrangement possibly caused by a chromothripsis event
Dual colour fluorescence in situ hybridization analysis of chromosome 16 and chromosome 12. FISH analysis using wcp12 (green) and wcp16 (red) probes (a) or RP11-485K18 (red) BAC probe, mapping to 12p11.2 and CEP12 (green), used as control probe (b), showed that the additional material present in the q arm of one chromosome 16 was derived from chromosome 12 and confirmed the pericentric inversion of one chromosome 12.