Table 2 Array-CGH and FISH findings in patients
Case No. | Array CGH result | Significant genes affected | FISH result |
|---|---|---|---|
1 | Loss of 12p13 (ETV6), no loss on RUNX1 | Loss of ETV6 | Rr, 1F - 92% |
2 | Loss of 12p13 (ETV6); no gain on RUNX1 | Loss of PAX5, ETV6, KRAS | NA |
3 | Loss of 12p13 (ETV6); no gain on RUNX1 | Loss of MLLT3, CDKN2A/B, MTAP, NOTCH1, BTG1, ETV6 | 3R, 1F - 55% 2R, 1F - 39% |
4 | Loss of ETV6 or RUNX1 was not found | Loss of MYB, JAK2, MLLT3, CDKN2A/B, MTAP | NA |
5 | Loss of 12p13 (ETV6); no loss on RUNX1 | Loss of ETV6 | Rr, 1F - 95% |
6 | Loss of ETV6 or RUNX1 was not found | Loss of MYB, MTAP, CDKN2A/B, | 2F, Rr, 1G - 60% Rr, 1F, 1G - 37% |
7 | Loss of 12p13 (ETV6); no gain on RUNX1 | Loss of MTAP, CDKN2A/B, ETV6, FHIT | NA |
8 | Loss of ETV6 or RUNX1 was not found | Appears normal | NA |
9 | Loss of ETV6 or RUNX1 was not found | Appears normal | Rr, 1G, 1F - 100% |
10 | Loss of ETV6 or RUNX1 was not found | Appears normal | NA |
11 | Loss of 21q22 (RUNX1); no loss on ETV6 | Loss of RUNX1 | NA |