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Table 1 Comparison of karyotyping, FISH and aCGH analysis (n = 86)

From: Array-based comparative genomic hybridization is more informative than conventional karyotyping and fluorescence in situ hybridization in the analysis of first-trimester spontaneous abortion

Case No Karyotype results FISH results Array CGH resultse
1–11 46, XX XX Normal
12–13a 46, XX XY Normal
14a 46, XX XY +5b
15–35 46, XY XY Normal
36 46, XY XY, +21 +21
37 46, XY XY +14b
38 47, XX, +3 XX +3
39 47, XX, +6 XX +6
40 47, XY, +6 XY +6
41 47, XX, +7 XX +7
42 47, XX, +8 XX +8
43 47, XX, +9 XX +9
44–45 47, XY, +12 XY +12
46 47, XX, +13 XX, +13 +13
47 47, XX, +14 XX +14
48 47, XX, +15 XX +15
49-53 47, XX, +16 XX, +16 +16
54-62 47, XY, +16 XY, +16 +16
63 47, XY, +16 XY, +16/XY mosaic +16
64 47, XX, +18 XX, +18 +18
65-66 47,XX,+20 XX +20
67-68 47,XX,+21 XX, +21 +21
69 47,XY,+21 XY, +21 +21
70-72 47,XX,+22 XX, +22 +22
73 47,XX,+22 XX,+22/XX mosaic +22
74 47,XX,+22 XX, +22 +9 b ,+22
75-77 47,XY,+22 XY, +22 +22
78 46,XY,del 18p XY del 18p
79 45,XY,-21 XY, -21 −21
80-81 45,X Monosomy X Monosomy X
82-84 Triploid Triploid Normal
85-86 Tetraploid c Normal Normal
All abnormal 47d 35 47
  1. aonly maternal cell cultured.
  2. bverified by QF-PCR.
  3. cdue to a culture artifact (92,XXXX and 92,XXYY).
  4. dexcluding two culture artifact tetraploids.
  5. eThe sex chromosome in aCGH was in accordance with FISH analysis.