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Table 1 Patient demographic and cytogenetic data

From: Analysis of ZAP70 expression in adult acute lymphoblastic leukaemia by real time quantitative PCR

Type Cytogenetics Cases M/F Agea ZAP70 expressionb Associated abnormalities
T-ALL   11 6/5 44.7; (19-56) 0.363; 0.252; (0.090-2.955) 9p abnormality(n = 5) 6q deletion (n = 2 t(10;14) (n = 1)
B-ALL   65 36/29 46.0; (18-79) 0.332; 0.185; (0.002-5.360)  
B-ALL t(9;22) 18 10/8 44.4; (23-70) 0.440; 0.191; (0.010-5.360) Hyperdiploid (n = 2), Monosomy 7 (n = 2) 9p abnormality (n = 3) 12p gain (n = 2) t(1;19) (n = 1)
B-ALL t(1;19) TCF3-PBX1 3 2/1 43.3; (42-52) 0.219; 0.210; (0.193-0.254) 9p abnormality (n = 2) 6q deletion (n = 2)
B-ALL 9p abnormality 12 8/4 45.2; (18-72) 0.180; 0.176; (0.004-0.535) Monosomy7 (n = 2) RUNX1 (n = 2) 12p abnormality (n = 3) 6q deletion (n = 2)
B-ALL Burkitt lymphoma 6 3/3 44.7; (22-78) 0.159; 0.168; (0.005-0.350) 12p abnormality (n = 1) 9p abnormality (n = 2)
B-ALL Hyperdiploid 6 5/1 45.9; (22-76) 0.232; 0.184; (0.004-1.383)  
B-ALL Monosomy 7 4 1/3 44.9; (37-58) 0.177; 0.182; (0.015-0.399) 12p abnormality (n = 1)
B-ALL Hypodiploid 3 1/2 43.7; (18-79) 0.173; 0.182; (0.067-0.290) 12p abnormality (n = 1)
B-ALL MLL/AFF1 1 1 30.0 0.089 12p abnormality
B-ALL Normal 46, XX or 46, XY 12 6/6 46.7; (18-82) 0.140; 0.100; (0.002-0.291)  
  1. a Mean patient age in years (range).
  2. b ZAP70 RNA expression was quantified by RT-qPCR and the normalised values expressed relative to that seen in Jurkat control cells. Data shown are mean, median and range for each sub-group.