Table 1 Patient demographic and cytogenetic data
From: Analysis of ZAP70 expression in adult acute lymphoblastic leukaemia by real time quantitative PCR
Type | Cytogenetics | Cases | M/F | Agea | ZAP70 expressionb | Associated abnormalities |
|---|---|---|---|---|---|---|
T-ALL | 11 | 6/5 | 44.7; (19-56) | 0.363; 0.252; (0.090-2.955) | 9p abnormality(n = 5) 6q deletion (n = 2 t(10;14) (n = 1) | |
B-ALL | 65 | 36/29 | 46.0; (18-79) | 0.332; 0.185; (0.002-5.360) | ||
B-ALL | t(9;22) | 18 | 10/8 | 44.4; (23-70) | 0.440; 0.191; (0.010-5.360) | Hyperdiploid (n = 2), Monosomy 7 (n = 2) 9p abnormality (n = 3) 12p gain (n = 2) t(1;19) (n = 1) |
B-ALL | t(1;19) TCF3-PBX1 | 3 | 2/1 | 43.3; (42-52) | 0.219; 0.210; (0.193-0.254) | 9p abnormality (n = 2) 6q deletion (n = 2) |
B-ALL | 9p abnormality | 12 | 8/4 | 45.2; (18-72) | 0.180; 0.176; (0.004-0.535) | Monosomy7 (n = 2) RUNX1 (n = 2) 12p abnormality (n = 3) 6q deletion (n = 2) |
B-ALL | Burkitt lymphoma | 6 | 3/3 | 44.7; (22-78) | 0.159; 0.168; (0.005-0.350) | 12p abnormality (n = 1) 9p abnormality (n = 2) |
B-ALL | Hyperdiploid | 6 | 5/1 | 45.9; (22-76) | 0.232; 0.184; (0.004-1.383) | |
B-ALL | Monosomy 7 | 4 | 1/3 | 44.9; (37-58) | 0.177; 0.182; (0.015-0.399) | 12p abnormality (n = 1) |
B-ALL | Hypodiploid | 3 | 1/2 | 43.7; (18-79) | 0.173; 0.182; (0.067-0.290) | 12p abnormality (n = 1) |
B-ALL | MLL/AFF1 | 1 | 1 | 30.0 | 0.089 | 12p abnormality |
B-ALL | Normal 46, XX or 46, XY | 12 | 6/6 | 46.7; (18-82) | 0.140; 0.100; (0.002-0.291) |