Centromeric association of small supernumerary marker chromosomes with their sister-chromosomes detected by three dimensional molecular cytogenetics

Table 4 Orientation of normal chromosomes 8, 15, 16, 18 and 19 to each other in cells with and without an sSMC.

	T - together [%]			N - nearby [%]			O - opposite [%]			number of nuclei
case	no sSMC	with sSMC	t-test	no sSMC	with sSMC	t-test	no sSMC	with sSMC	t-test	no sSMC	with sSMC
1	43	56	P < 0.003	57	36	nsd	0	8	P < 0.001	42	78
2	n.a.	4	n.a.	n.a.	82	n.a.	n.a.	4	n.a.	n.a.	23
3	42	40	nsd	58	51	nsd	0	9	P < 0.001	26	79
5	28	30	nsd	66	17	P < 0.001	6	53	P < 0.001	100	41
4 and 5	36	28	P < 0.006	52	36	P < 0.002	12	36	P < 0.002	50	71
1 to 5	28	12	P < 0.002	66	62	nsd	6	26	P = 0.001	100	69
	67	73	nsd	31	25	nsd	2	2	nsd	174	259

ISSN: 1755-8166