Centromeric association of small supernumerary marker chromosomes with their sister-chromosomes detected by three dimensional molecular cytogenetics

Table 3 Position of normal chromosomes 8, 15, 16, 18 and 19 in cells with and without an sSMC.

	P - periphery [%]			I - intermediate [%]			C - central [%]			number of nuclei
case	no sSMC	with sSMC	t-test	no sSMC	with sSMC	t-test	no sSMC	with sSMC	t-test	no sSMC	with sSMC
1	21	32	nsd	45	42	nsd	34	26	nsd	42	84
2	n.a.	44	n.a.	n.a.	31	n.a.	n.a.	40	n.a.	n.a.	36
3	28	53	P < 0.001	42	24	P < 0.002	30	23	P = 0.007	40	52
5	63	55	nsd	25	39	yes P = 0.002	12	6	nsd	52	69
4 and 5	65	61	nsd	27	31	nsd	8	8	nsd	52	108
1 to 5	12	13	nsd	38	39	nsd	50	48	nsd	133	274

ISSN: 1755-8166