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Figure 1 | Molecular Cytogenetics

Figure 1

From: An unusual T-cell childhood acute lymphoblastic leukemia harboring a yet unreported near-tetraploid karyotype

Figure 1

Cytogenetic and molecular analysis. A Partial and total G-banding karyotype showing a near-tetraploidy (mn 94); B RT-PCR results showing ETV6-RUNX1 fusion gene negative. cDNA of a health donor (DONOR) was used as negative (12;21) control for ETV6-RUNX1 fusion C M-FISH showing the karyotype: 94, XXYY, i(17)(q10)x2,+20,+20; D FISH cep 17 and LSI p53 showing the deletion of 2 copies of P53 gene on derivatives i(17q).

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