Table 3 Association of ERBB2 and EGFR gene amplification with clinicopathological parameters in 69 cases of gastric cancer

Sex

Male

41

8(19.5)

0.316

0.574

11(26.8)

0.261

0.609

Female

28

4(14.3)

6(21.4)

Age

≥ 60

36

7(19.4)

0.221

0.638

10(27.8)

0.400

0.527

< 60

33

5(15.2)

7(21.2)

Histological type

Papillary adenocarcinoma

16

2(12.5)

3(18.8)

Tubular adenocarcinoma

14

2(14.3)

3(21.4)

Mucinous adenocarcinoma

15

3(20.0)

0.729

0.948

4(26.7)

0.714

0.950

Poorly differentiated adenocarcinoma

13

3(23.1)

4(30.8)

Signet ring cell carcinoma

11

2(18.2)

3(27.3)

Gastric cancer staging

T1/T2

25

1(4.0)

4.894

0.027

2(7.7)

5.845

0.016

T3/T4

44

11(25.0)

15(34.1)

Lymph node metastasis

Present

41

10(24.4)

6.264

0.012

14(34.1)

4.920

0.027

Absent

28

2(7.1)

3(10.7)