Scion Image signal intensity measurement. In interphase it is obvious that there is a CNV but no duplication of the signal RP11-96G1 produces. This is a typical pattern as observed in all up to now studied CNV-specific BACs [4, 12]. Applying Scion Image (Scion Corp: http://en.bio-soft.net/draw.html) signal intensity measurement was done, revealing an approximate duplication of signal intensity on the 'derivative' chromosome 8. The arrowhead highlights the larger signal in case 2.