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Table 1 The chromosome instability of peripheral blood lymphocytes in P1, P2, and their parents, after studying by conventional and banding cytogenetic methods

From: Two siblings with immunodeficiency, facial abnormalities and chromosomal instability without mutation in DNMT3B gene but liability towards malignancy; a new chromatin disorder delineation?

Patient Age at the time of blood sampling Culture/
chromosome staining
Totally cells scored Aberrations frequency (%)
P 1 5 years 6 months 72 h/solid (standard) 147 23
(15.6 ± 3.16)
  6 years 2 months 48 h/solid (standard) 132 32
(24.24 ± 3.73)
  6 years 2 months 48 h/GTG 253 83
(32.81 ± 2.95)
  7 years 10 months 72 h/GTG 306 68
(22.22 ± 2.38)
P 2 1 year 8 months 96 h/GTG 35 14
(40.0 ± 8.28)
  4 years 4 months 72 h/GTG 200 19
(9.5 ± 2.77)
Mother 39 years 72 h/GTG 197 6
(3.05 ± 1.31)
Father 38 years 72 h/solid standard 200 16
(8.0 ± 1.92)
  41 years 72 h/GTG 100 4
(4.0 ± 1.96)